Zebra ZD421 Driver, Software, Manual

Zebra ZD421 Driver is an advanced desktop printer that offers all what you need from a printer covering features, flexibility, reliability and security. It is a 4-inch desktop printer that build on legacy of popular GK series from Zebra. Thus, it has more capabilities and security messages to setup the users in the later years.

The advanced features includes the new and more intuitive interfaces, powerful architecture and field-upgradeable wireless kit. The ZD421 label printer meets a big variety of application requirements due to the use of thermal transfer, direct thermal, health care and ribbon cartridge model.

Designed to be a powerful engine, here are what you can get to know in detail about it.

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Simple and Easy To Use

The ZD421 label printer is simple and easy to use due to a number of advanced features added including the new media guide and media handling designs to make the regular operation even easier. Truly, the ZD421 engine has more intuitive and powerful operation, making it just simple and easy to use.

Highly Flexible

To elevate your expectation, Zebra ZD421 comes with multiple models to meet your needs. In this regards, it is available in direct thermal, thermal transfer and healthcare as well as ribbon cartridge models. Hence, the engine will be able to meet a wide variety of applications.

Printing Performance

As we have stated, Zebra ZD421 Driver is primarily designed to handle advanced technology for printing labels. Due to the innovative architecture feature, the engine is predicted to be ready to use in the future.

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Compared to ZD420, this type is 30% more powerful. Meanwhile, it can be 700% more powerful than GK series. This enables you to handle more tasks and perform more operation all together as well as maintain the security. In short, this type of label printer will be ready for what’s next.


Zebra ZD421 Driver can be integrated with your existing wired and wireless networks. Alternatively, you can also use the standard USB and USB Host to directly connect it to the PC. This way, ZD421 offers Ethernet, serial and dual wireless radio along with fast 802.11ac Wi-Fi and Bluetooth 4.1.

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Due to the printer’s compatibility, you are allowed to print from any Windows, Android or iOS device. Just make sure that you run the Zebra printer’s setup mobile app by using the Bluetooth Low energy (BLE). You may also use Print Touch tag to pair and print simply and easily.

Zebra ZD421 for Windows

Supported Platform: Win 10 (32-bit/64-bit), Win 8 (32-bit/64-bit), Win 8.1 (32-bit/64-bit), Win 7 (32-bit/64-bit), Win XP (32-bit/64-bit), Win Server, Win Vista

Zebra ZD421 for macOS

Supported Platform: mac 10.3, mac 10.4, mac 10.5, mac 10.6, mac 10.7, mac 10.8, mac 10.9, mac 10.10, mac 10.11, mac 10.12, mac 10.13, mac 10.14, mac 10.15, mac 11

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Zebra ZD421 Manual Download

Stella Nelson

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